About Lefra 10 Tablet 10

Lefra-10 Tablet is used to treat rheumatoid arthritis and psoriatic arthritis by reducing inflammation and preventing joint damage. It suppresses the immune system to decrease inflammation and prevent further damage. It belongs to the disease-modifying antirheumatic drugs (DMARDs) group of medicines.

In addition to its main use, this medicine can also help in reducing inflammation, joint pain, swelling and damage caused by these autoimmune conditions. It targets your immune system directly by suppressing its overactive responses.

Uses of Lefra 10 Tablet 10

Lefra-10 Tablet is used for the following conditions:

• Managing active rheumatoid arthritis: This is a chronic inflammatory disorder that can affect more than just your joints. In some people, it can damage a wide variety of body systems, including the skin, eyes, lungs, heart and blood vessels.

• Controlling active psoriatic arthritis: This condition causes inflammation of your joints and is closely linked with psoriasis, a skin condition. It typically leads to pain, stiffness and swelling in and around your joints.

How Lefra 10 Tablet 10 Works?

Lefra-10 Tablet contains leflunomide (10 mg), which acts on your body in the following ways:

• Inhibits Dihydroorotate Dehydrogenase: Leflunomide works by blocking your body's enzyme called dihydroorotate dehydrogenase. This enzyme plays a vital role in synthesising pyrimidine ribonucleotide uridine monophosphate (rUMP), which is required to grow and reproduce rapidly dividing cells.

• Reduces Inflammation: By inhibiting this enzyme, leflunomide effectively interferes with the production of DNA and RNA, essential for rapidly dividing cells such as activated T lymphocytes involved in rheumatoid arthritis. This action reduces inflammation and helps manage symptoms.

Directions for Use of Lefra 10 Tablet 10

Here are the instructions to follow while taking Lefra-10 Tablet:

• Follow the precise dosage and timing instructions provided by your doctor.

• Do not change or exceed the prescribed dose without consulting your doctor.

• Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.

• Adhere to the dietary recommendations given by your doctor.

Side Effects of Lefra 10 Tablet 10

Lefra-10 Tablet may cause the following side effects:

• Diarrhoea

• Alopecia: This is a condition in which you might experience hair loss.

• Elevated liver enzymes: This could indicate potential damage to your liver.

• Rash

• Hypertension: This refers to high blood pressure, which can lead to serious heart problems if left unchecked.

• Thrombocytopaenia: This is a condition that causes low platelet count in your blood, which could lead to bruising and slower clotting after an injury.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Lefra-10 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some simple ways to manage a couple of common side effects:

• Diarrhoea: Drink plenty of healthy fluids to stay hydrated and follow the diet recommended by your doctor.

• Rash: Apply a cold compress to the affected area to reduce itching and inflammation. If the rash persists or worsens, consult your doctor.

Dosage of Lefra 10 Tablet 10

• Daily Dose

You should take the daily dose of Lefra-10 Tablet as directed by your doctor. Your dosage may vary depending on certain factors such as the severity of your symptoms and how you respond to the medicine. It's vital to take the medicine as prescribed. You must not increase your dosage without discussing it with your doctor.

• Over Dose

If an overdose occurs, it could lead to common side effects like diarrhoea, rash, and hair loss. In case you suspect an overdose, inform your doctor promptly so that they can provide appropriate advice.

• Missed Dose

If you forget to take your regular dose of Lefra-10 Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Do not double your dosage to